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Please help me to translate it into Ch! Thank you!

In a round-bottomed 2 L flask equipped with a magnetic stirrer and placed under an inert atmosphere, there was added 750 mL anhydrous THF, containing 30 g LAH. There was then added, in THF solution, 60 g 2,5-dimethoxy-beta-nitrostyrene. The final solution was a dirty yellow-brown color, and it was kept at reflux temperature for 24 h. After cooling, the excess hydride was destroyed by the dropwise addition of IPA. Then 30 mL 15% NaOH was added to convert the inorganic solids to a filterable mass. The reaction mixture was filtered and the filter cake washed first with THF and then with MeOH. The combined mother liquors and washings were freed of solvent under vacuum and the residue suspended in 1.5 L H2O. This was acidified with HCl, washed with with 3x100 mL CH2Cl2, made strongly basic with 25% NaOH, and reextracted with 4x100 mL CH2Cl2. The pooled extracts were stripped of solvent under vacuum, yielding 26 g of oily residue, which was distilled at 120-130 °C at 0.5 mm/Hg to give 21 g of a white oil, 2,5-dimethoxy-phenethylamine (2C-H) which picks up carbon dioxide from the air very quickly. 

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  • 2009-10-16 22:50:13
    将磁力搅拌器放入一个2L的圆底烧瓶,放置在惰性气体环境下。加入750ml无水THF,包括30gLHA。这时候,再在THF溶液中加入60g2,5-二甲氧基-β-硝基苯乙烯。最后溶液呈土黄棕色,将其保持在回流温度下24h。待冷却后,用外加物异丙醇滴定多余的氢化物。然后加入20ml15%氢氧化钠以溶解无机固态沉淀。反应混合物率过后,将滤后成沉淀先用THF洗涤让后用MeOH(甲醇)。母液和洗涤物的混合物在真空环境下无法相溶,而且将残渣放置在1.5l水中。这是被盐酸酸化,用3*100ML二氯甲烷浸湿,制作加油25%氢氧化钠和用4*100ml的二氯甲烷再萃取。萃取物的混合溶剂在真空环境下脱水蒸馏,得到26g油性残留物,它在120 - 130°C0.5毫米汞柱压强下蒸馏可以得到21克白色的液体石蜡,2,5-二甲氧基-苯乙胺(2C-H),可迅速吸收空气中二氧化炭。

    爱***

    2009-10-16 22:50:13

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